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Wellbutrin and finger/joint pain

Original Post
Short Fall Sean · · Bishop, CA · Joined Sep 2012 · Points: 7

I'm writing this as a note of caution to other climbers and also out of curiosity if anyone else has experienced something similar. A couple of months ago I started taking Wellbutrin (Bupropion) at a fairly low dose of 150mg/day. I'm not sure of the exact timing, but sometime fairly soon after that I developed an intense aching in my fingers after climbing. At one point it was bad enough that I decided to take several days off, and after 5 days of no climbing, the pain was still there, albeit at a somewhat lower level. It wasn't for almost two months that I realized - while biking home from the gym with throbbing fingers - that the pain had started shortly after starting the medication. I stopped taking it right away, and in the week or so since then, the pain has completely gone away. 

I looked it up, and joint pain is a common side effect of Wellbutrin, but it wasn't one that was mentioned to me when I started taking it. Apparently it usually goes away after a few weeks, but it persists indefinitely in a small number of people. I've always had dodgy fingers, and I've had several pulley injuries, so I'm probably primed for general achiness, but it was pretty dramatic how much they were hurting. I thought I had suddenly developed early arthritis (I'm 42) and was going to have to quit climbing. 

Desert Rock Sports · · Las Vegas, NV · Joined Aug 2019 · Points: 2

That sucks!

Other common meds can have pretty terrible side effects too... Reminder about Cipro:
"Taking ciprofloxacin increases the risk that you will develop tendinitis (swelling of a fibrous tissue that connects a bone to a muscle) or have a tendon rupture (tearing of a fibrous tissue that connects a bone to a muscle) during your treatment or for up to several months afterward." - Ciprofloxacin @ medlineplus.gov

WF WF51 · · Unknown Hometown · Joined Oct 2020 · Points: 0

Delayed hypersensitivity serum sickness-like reaction. Well-known, well documented.  It's mentioned in the package insert, in the Precautions section. 

Spencer Moore · · Bellingham · Joined Jun 2019 · Points: 133

I'm on three months of Wellbutrin and my old wrist injury is magically reemerging. Sadness because bad brain juices or sadness because bad wrist tendons... Not sure if the two are related in my case though, as it's a previous injury. This is the magic of the bell curve of medication side effects, it causes constipation AND diarrhea, weight gain AND weight loss. It's like saying "we know that this drug will do something and that includes all types of things that occur from being alive".

Steve Williams · · The state of confusion · Joined Jul 2005 · Points: 235

One shouldn't take wellbutrin if you've had a concussion. . . 

WF WF51 · · Unknown Hometown · Joined Oct 2020 · Points: 0

It would be nice if a drug will do only what's desired, e.g., an SSRI won't bind to cholinergic or histamine receptors, won't affect platelet serotonin, ACE inhibitors wouldn't cause angioedema. But the science of pharmacology isn't there yet. 

Guideline #1: Don't be a jerk.

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